Currently working on - unpublished

An epigenome targeted CRISPR screen identifies key stage-specific determinants of human erythropoiesis
Goksel E, Ozcan SC et al.
Research, 2027
PFKFB2 modulates ferroptosis sensitivity in pancreatic cancer
Altunok TH, Ozcan SC et al.
Research, 2026
Stress-driven strategic games in cancer
Ozcan SC
Review, Perspective, 2026

Pre-prints

Proximity labeling reveals cell cycle-specific NEK2 interactions and a regulatory axis controlling NUSAP1 stability
Cicek E, Ozcan SC, Kanevetci B, Kalkan B, Ozkan NE, Ozlu N, Acilan C
bioRxiv, 2026
Stress adaptation pathways and HA-CD44 signaling maintain the survival of pancreatic cancer cells with centrosome amplification
Ozcan SC, Goksel E, Kalkan BM, Cicek E, Kanevetci B, Acilan C
bioRxiv, 2026
RESTRICT-seq enables time-gated CRISPR screens and uncovers novel epigenetic dependencies of SCC resistance
Ozcan SC, Amador DG, Powers JA, Njiru AG, Ansari Z, Woappi Y
bioRxiv, 2025

Research Articles

Epidrug screening identifies type I PRMT inhibitors as modulators of lysosomal exocytosis and drug sensitivity in cancers
Sergi B, Yuksel-Catal N, Ozcan SC, Syed H, Duvvuri U, Kiselyov K, Acilan C
Cell Death & Disease, 2025
Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical centrosome linker proteins
Ozcan SC, Kalkan BM, Cicek E, Canbaz AA, Acilan C
Scientific Reports, 2024
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction
Kalkan BM, Ozcan SC, Cicek E, Gonen M, Acilan C
Cell Death & Disease, 2024
Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS-transformed pancreatic cells
Ozcan SC, Mutlu A, Altunok TH, Gurpinar Y, Sarioglu A, Guler S, Muchut RJ, Iglesias AA, Celikler S, Campbell PM, et al.
Biochemical and Biophysical Research Communications, 2021
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
Ozcan SC, Sarioglu A, Altunok TH, Akkoc A, Guzel S, Guler S, Imbert-Fernandez Y, Muchut RJ, Iglesias AA, Gurpinar Y, et al.
Molecular and Cellular Biochemistry, 2020
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro
Yalcin A, Solakoglu TH, Ozcan SC, Guzel S, Peker S, Celikler S, Balaban BD, Sevinc E, Gurpinar Y, Chesney JA
Biochemical and Biophysical Research Communications, 2017
6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27
Yalcin A, Clem BF, Imbert-Fernandez Y, Ozcan SC, Peker S, O'neal J, Klarer AC, Clem AL, Telang S, Chesney J
Cell Death & Disease, 2014

Reviews & Perspectives

Keep Calm and Carry on with Extra Centrosomes
Kalkan BM, Ozcan SC, Quintyne NJ, Reed SL, Acilan C
Cancers, 2022

Select Conference Papers

Identification of chromatin regulators required for enucleation
Goksel E, Ozcan SC, Kayabolen A, Yalcin O
Blood, 2023
A deep learning model for automated segmentation of fluorescence cell images
Aydın M, Kiraz B, Eren F, Uysallı Y, Morova B, Ozcan SC, Acilan C, Kiraz A
Journal of Physics: Conference Series, 2022

PhD Thesis

The role of PFKFB2 on oncogenic transformation of pancreatic epithelial cells
Ozcan SC
Uludag University, 2018